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br Chondroitin sulfate proteoglycans CSPGs are major compone
2019-07-02

Chondroitin sulfate proteoglycans (CSPGs) are major components of the extracellular matrix in cartilage. Each CSPG comprises a single core protein and attached chondroitin sulfate (CS), belonging to the glycosaminoglycan family of sugar chains. CSPGs and CS are involved in numerous biological and
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A structured inherited arrhythmia or heart disease
2019-07-01

A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli
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The patient had experienced cardiopulmonary arrest because o
2019-07-01

The patient had experienced cardiopulmonary arrest because of PEA and bradycardia at least twice while on oral treatment for variant angina, but neither ventricular fibrillation nor ventricular tachycardia was apparent. Spontaneous attacks occurred despite the use of an oral calcium blocker, and low
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br Conflict of interest br Introduction Idiopathic left
2019-07-01

Conflict of interest Introduction Idiopathic left ventricular tachycardia (ILVT) with a right bundle-branch block (RBBB) configuration and superior or left axis is a distinct entity that arises in the left ventricle, mostly because of a reentry mechanism and is usually verapamil sensitive [1–6
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An ERP in the ECG has been shown to be
2019-07-01

An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A
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El juego de las apariencias y la obtenci n
2019-07-01

El juego de las apariencias y la obtención de un estatus no son privativos de los consumidores del arte en este texto: coleccionistas, guías de museo o críticos improvisados. El cuento “Borges y el ultraísmo”, también del libro Amores de segunda mano (1991), ubicará la discusión directamente en los
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However transparency has declined rather than improved A
2019-07-01

However, transparency has declined rather than improved. A recent analysis in the ranked PEPFAR as very poor—50th of 67 aid agencies worldwide. The report noted that, “PEPFAR does not disclose information on contracts to prime partners and sub-partners in a machine-readable and open format consiste
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Desde las organizaciones sociales y poblaciones movilizadas
2019-07-01

Desde las organizaciones sociales y poblaciones movilizadas, estas protestas marcan el inicio de un nuevo periodo de distanciamiento frente Tasquinimod molecular los actores político-institucionales, en particular el Partido Nacionalista que logró aglutinar electoralmente sus críticas y expectativas
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Un ciclo diferente y mucho m s profundo
2019-07-01

Un ciclo diferente y mucho más profundo de transformaciones se inicia con el proceso constitucional en Bolivia y Ecuador. Bolivia se “re-funda” en 2009 y se proclama Estado Unitario Social de Derecho Plurinacional Comunitario. El capítulo cuarto sobre los derechos de las naciones y pueblos indígenas
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Leptin synthesized in adipocytes is a regulator of fat metab
2019-07-01

Leptin, synthesized in adipocytes, is a regulator of fat metabolism and reproduction [7]. The levels of leptin correlate with body fat mass and show a wide variation in individuals. In the bone marrow microenvironment, the leptin secreting adipocytes occupy a significant part [8]. Leptin stimulates
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br Clinical characteristics Brugada syndrome is
2019-06-29

Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn
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Involvement of the ventricular myocardium can
2019-06-29

Involvement of the ventricular myocardium can lead to delayed conduction or anatomical obstacles that are labile to ventricular tachyarrhythmia. Arrhythmias are independently predictive of sudden cardiac death (SCD) [9]. SCD is common in patients with cardiac AL amyloidosis, and prophylactic implant
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br Radiotherapy for bone metastases As
2019-06-29

Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief
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Consequently in asymptomatic individuals multiple and repeat
2019-06-29

Consequently, in asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. Moreover, in addition recording at higher lead
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br Comments Fig shows regular narrow QRS tachycardia
2019-06-29

Comments Fig. 1 shows regular narrow QRS tachycardia with approximate GW9508 rate of 130/min; ST elevations were recognized in leads V1–V4 and P wave appeared to be recorded by lead V1, but the other leads recorded positive large waves before each QRS complex. When observing an electrocardiogram
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