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The effects of zoledronic acid
2019-05-15

The effects of zoledronic LJI308 are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Whereas
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br Patients and methods br Results
2019-05-15

Patients and methods Results Discussion In the ZOTECT study, ZOL therapy was associated with significantly decreased P1NP and CTX levels within 1 month of initiating treatment (Pin AMD3100 with data from a small trial in patients with newly diagnosed bone metastases from PC, BC, or lung ca
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Adhesive interactions Adhesive interactions between myeloma
2019-05-15

Adhesive interactions: Adhesive interactions between myeloma ABT-737 and stromal cells play a significant role in both the homing of MM cells to the bone marrow and augmentation of the bone destructive process. These adhesive interactions result in activation of NF-κB and p38 MAP-kinase signaling,
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Initial bone marrow biopsy was inadequate in
2019-05-14

Initial bone marrow biopsy was inadequate in size for detailed examination and had severe crush artifact. The preserved focus of marrow showed hypercellularity with large, multinucleated, dysplastic megakaryocytes and megaloblastoid changes in erythroid series (Fig. 1B and C). There was no increase
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Leong et al reported a similar case
2019-05-14

Leong et al. reported a similar case of a short circuit in the Riata 1570 defibrillator lead, which manifested as unsuccessful defibrillation [10]. In this case, product analysis of generator indicated structural device damage owing to a short circuit in the defibrillation lead. Marenco et al. also
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The patient started FOLFOX chemotherapy at another
2019-05-14

The patient started FOLFOX chemotherapy at another institute on September 14, 2015. However, he suddenly lost consciousness and his blood pressure plummeted; the electrocardiogram monitor showed ventricular tachycardia. After cardiopulmonary resuscitation, he regained spontaneous circulation and was
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br Acknowledgments The authors would
2019-05-14

Acknowledgments The authors would like to thank Sarah Mack for technical assistance with the histology and IHC. We would also like to acknowledge Dr. Gregory Dieudonne in the Department of Musculoskeletal Radiology, University of Rochester Medical Center for advice and assistance in manuscript wr
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br Discussion br Conflict of interest br Introduction Device
2019-05-14

Discussion Conflict of interest Introduction Device implantations may be challenging in patients with venous abnormalities. The most common congenital variation, frequently associated with other congenital abnormalities, is a persistent left superior vena cava (PLSVC), and successful atrial
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El resultado de esta reuni
2019-05-14

El resultado de esta reunión se plasmó en una serie de resoluciones que transcribe Elena Aub en su libro sobre el me/59. En resumen, se acordaba un programa de máximos para España en el que se señalaba el restablecimiento de todas las libertades políticas, el derecho de autodeterminación de Cataluña
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Una de las teor as m s
2019-05-13

Una de las teorías más destacadas sobre el género lo emparenta con el proyecto que llevaron estrone cabo autores alemanes como Bertold Brecht o Walter Benjamin, quienes: Ana María Amar Sánchez, teórica que propone esta línea genealógica para explicar la creación testimonial del argentino Rodolfo Wa
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GSK-3 Inhibitor IX There are limitations to the current stud
2019-05-13

There are limitations to the current study. As with all surveys, there is an inherent bias in those that are contacted and in those that respond. Obtaining 90 responses on this topic is clearly important, however, the study would be strengthened by a greater number of responses. In addition, the maj
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br Conclusion br Conflict of interest
2019-05-13

Conclusion Conflict of interest Introduction Future challenges and conclusion In recent decades several anticancer drugs have been approved for the management and treatment of colorectal cancer. These drugs do not represent a revolution in the treatment of CRC. However, 5-FU has continue
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br The estimated number of women who die each year
2019-05-13

The estimated number of women who die each year from causes related to pregnancy or childbirth has dropped substantially—from 543 000 deaths in 1990 to about 287 000 in 2010. Nevertheless, maternal mortality ratios remain among the least equitable of all health indicators, ranging from less than f
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Seg n Auerbach la parataxis
2019-05-13

Según Auerbach, la parataxis es un modo primitivo y anticlásico de narrar, típico de la Edad Media, que será sustituido gradualmente por maneras más modernas y finas de describir la realidad. No obstante, en fechas recientes ha vuelto direct thrombin inhibitors ser practicada, por ejemplo por una se
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Pero todo cambia despu s del exilio en Francia
2019-05-13

Pero todo cambia después del exilio en Francia; son los presuntos “bárbaros” los únicos que parecen ser capaces de una auténtica revolución: dirá Bilbao con admiración que ellos fueron los que en 1848 hicieron purchase eletriptan hydrobromide las “naciones de Europa […] estremecerse como bajo las pl
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