• br Acknowledgments The authors would like to acknowledge

  2018-11-05

  

  Acknowledgments The authors would like to acknowledge their funders, the Bill and Melinda Gates Foundation (Grant No. A121947), in supporting this work. In addition, the authors would like to thank Emily Treleaven and Kanksha Singh for helping with data collection activities. Background Follo

• Table illustrates the Hispanic paradox in birth outcomes

  2018-11-05

  

  Table 2 illustrates the Hispanic paradox in birth outcomes. Panel A uses the records of children born between 1970 and 1985 and reports the differences between children (G2) of first-generation Hispanic women and children of white mothers born in the U.S. Panel B uses the records of children born be

• br Funding and conflict of interest

  2018-11-05

  

  Funding and conflict of interest statements Acknowledgements We would like to acknowledge funding received from the Canadian Institutes of Health Research (award number GSD-134926) and the Lawson Foundation, Canada (grant number GRT 2011-013). We would also like to thank Dr. Mieke Koehoorn for

• The current study must be interpreted within

  2018-11-05

  

  The current study must be interpreted within the context of its strengths and potential limitations. A strong point is that we measured both dp-ucMGP and t-ucMGP in a relatively large sample representative of the Flemish population and that we replicated the inverse association of eGFR or chronic ki

• We also revealed that Scd is a functional

  2018-11-05

  

  We also revealed that Scd1 is a functional target of miR-378 that promotes lipolysis in adipose tissues of miR-378 Tg mice. SCD1 critically regulates lipid metabolism, and dysregulation of SCD1 activity results in various metabolic disorders, including diabetes, cardiovascular disease, and obesity (

• br Author Contributions br Conflicts

  2018-11-05

  

  Author Contributions Conflicts of Interest Acknowledgments Introduction ADAMs (a disintegrin and metalloproteinases) are multifunctional proteins involved in ectodomain shedding of transmembrane proteins and thereby regulate cell adhesion, migration, and cell–cell communication. Ectodoma

• Dengue is a climate sensitive mosquito borne viral disease t

  2018-11-05

  

  Dengue is a climate sensitive mosquito-borne viral disease that is generally found in the tropics and subtropics (Murray et al., 2013). According to the World Health Organization (World Health Organization (WHO), 2012) and recent assessment on global burden of diseases (GBD2013) (Murray et al., 2015

• p97 br Skin and Hair Aging Lifestyle and the

  2018-11-05

  

  Skin and Hair Aging, Lifestyle and the Skin and Scalp Microbiomes William W. Mohn (Vancouver, Canada) reported on a cross-sectional study investigating the skin and scalp microbiome in relation to skin and hair aging and lifestyle, and involving 495 subjects 10–78years of age. Diversity of the sc

• However one might question whether

  2018-11-05

  

  However, one might question whether effective compounds that do not bind to the C-terminal domain of PrP or that have other molecular targets besides PrP () will be excluded from this virtual screening. In the first case, docking with at least the 90–231 domain of the prion protein will prove useful

• Our previous study demonstrated that HDAC

  2018-11-05

  

  Our previous study demonstrated that HDAC inhibition contributed to the anticancer effect of statins (Lin et al., 2008). Combining anti-cancer drugs with different mechanisms is a rational approach to improve efficacy. JMF3086, synthesized to inhibit both HDACs and HMGR, exhibits significant benefit

• myc inhibitor We first demonstrate that in

  2018-11-05

  

  We first demonstrate that, in addition to including multiple layers of data, aSICS outperforms a standard method in terms of consistency between two glioma data sets. Next, we use aSICS to build a multi-layered model of regulation of glioma subtypes. Our model identifies both known and novel regulat

• Disclosures br Acknowledgements Research performed

  2018-11-05

  

  Disclosures Acknowledgements Research performed in our laboratories is supported by the University of Franche-Comté, the Agence Nationale de Recherches sur le Sida et les Hepatites Virales (ANRS, n°13543 and 13544) and HIVERA 2013 (EURECA project). In this issue of , Venner and co-authors ex

• secretin receptor The fit of the structural model was good s

  2018-11-05

  

  The fit of the structural model was good (see Table 2) and confirms the hypotheses related to the direct influence of parental levels of regional ethnocentrism on children\'s levels of ethnocentrism and the hypotheses related to the influence of parental levels of regional identity on the children\'

• Using independent spatial descriptions for solving the forwa

  2018-11-05

  

  Using independent spatial descriptions for solving the forward problem and doing the inversion step raises the following challenge. Not only need information to be transferred from the external forward codes into ASKI (as described above), but also information about the new model derived in an itera

• Interestingly DBS in the medial

  2018-11-05

  

  Interestingly, DBS in the medial or intralaminar thalamus is being used with great success for the treatment of Tourette׳s syndrome [82,83]. One side effect of intralaminar thalamus DBS for Tourette׳s syndrome is profound fatigue. The parameters of stimulation typically include 24h stimulation at hi

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